This is the human assembly made by the T2T project called CHM13 V2.0. It
contains sequences for centromeres and other difficult to sequence regions and has no
gaps. If you are new to genomics or unsure about which assembly to use, 
note that the improvements concern regions of the genome that are not
yet important for most analyses or diagnostic purposes.

This is not the human genome reference sequence released by the Genome
Reference Consortium GRCh38 (aka hg38), which is used by most databases,
aligners and diagnostics labs at the moment.  If you are looking for the
current human reference sequence then you may want to use
https://hgdownload.ucsc.edu/goldenPath/hg38/bigZips/ rather than basing your
analysis on CHM13.

Files:

hs1.fa.gz - "Soft-masked" assembly CHM13 sequence in one file.
    Repeats from RepeatMasker and Tandem Repeats Finder (with period of 12 or
    less) are shown in lower case; non-repeating sequence is shown in upper
    case.

hs1.2bit - contains the complete human CHM13 genome sequence
    in the 2bit file format.  Repeats from RepeatMasker and Tandem Repeats
    Finder (with period of 12 or less) are shown in lower case; non-repeating
    sequence is shown in upper case.  The utility program, twoBitToFa (available
    from the kent src tree), can be used to extract .fa file(s) from
    this file.  A pre-compiled version of the command line tool can be
    found at:
        http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/
    See also:
        http://genome.ucsc.edu/admin/git.html
        http://genome.ucsc.edu/admin/jk-install.html

hs1.repeatMasker.out - RepeatMasker .out file.  RepeatMasker was run with the
    -s (sensitive) setting.

hs1.repeatMasker.version.txt - version of repeatmasker that was used.

genes/hs1.ncbiRefSeq.gp.gz - gene annotations made by NCBI RefSeq in UCSC genePred format.

genes/hs1.ncbiRefSeq.gtf.gz - gene annotations made by NCBI RefSeq in GFF/GTF format.

      Name                                  Last modified      Size  Description
      Parent Directory                                           -   
      hs1.repeatMasker.version.txt          2022-02-04 10:35  922   
      hs1.chrom.sizes.txt                   2022-06-22 21:16  375   
      hs1.2bit                              2022-07-16 14:27  775M  
      hs1.untrans.gfidx                     2022-07-16 14:32  2.1G  
      hs1.trans.gfidx                       2022-07-16 14:33  4.6G  
      hs1.2bit.bpt                          2022-07-16 14:50  3.3K  
      hs1.chromAlias.txt                    2022-07-18 11:38  866   
      hs1.chromAlias.bb                     2022-07-18 11:38   43K  
      hs1.repeatMasker.out.gz               2022-07-18 11:48  173M  
      THIS_IS_GENOME_ASSEMBLY_T2T-CHM13v2.0 2022-07-18 12:06    0   
      hs1.fa.gz                             2022-07-18 12:08  930M  
      GCA_009914755.4_assembly_report.txt   2022-08-11 03:26  3.4K  
      md5sum.txt                            2022-09-15 11:21  658   
      genes/                                2023-08-30 15:16    -