This file is from:

This directory contains conservation scoring by phyloP (phylogenetic p-values)
from the PHAST package ( for multiple
alignments of 29 genome sequences to the human genome.

Files in this directory:

    hg38.30way.phyloP/*.wigFix.gz - scores in fixed step wiggle format
    hg38.phyloP30way.mod - phyloP tree model with branch lengths for
                            all 30 species - scores in bigWig format
    md5sum.txt - MD5 checksums to verify download files

See also:
   for bigWig format description

For a description of the fixed step wiggle data file format, see:

The phastCons data can be found at:

The multiple alignments and methods description are at:

For more information about this data, see the track
description for the Conservation track:

Assemblies used in these alignments:         (alignment type)

Human - Homo sapiens
                Dec. 2013 (GRCh38/hg38) (reference)
Angolan colobus - Colobus angolensis palliatus
                Mar. 2015 (Cang.pa_1.0/colAng1) (syntenic)
Armadillo - Dasypus novemcinctus
                Dec. 2011 (Baylor/dasNov3) (syntenic)
Baboon - Papio anubis
                Feb. 2013 (Baylor Panu_2.0/papAnu3) (reciprocal best)
Black lemur - Eulemur macaco
                Aug. 2015 (Emacaco_refEf_BWA_oneround/eulMac1) (reciprocal best)
Black snub-nosed monkey - Rhinopithecus bieti
                Aug. 2016 (ASM169854v1/rhiBie1) (reciprocal best)
Bonobo - Pan paniscus
                Aug. 2015 (MPI-EVA panpan1.1/panPan2) (syntenic)
Bushbaby - Otolemur garnettii
                Mar. 2011 (Broad/otoGar3) (syntenic)
Chimp - Pan troglodytes
                May 2016 (Pan_tro 3.0/panTro5) (syntenic)
Coquerel's sifaka - Propithecus coquereli
                Mar. 2015 (Pcoq_1.0/proCoq1) (syntenic)
Crab-eating macaque - Macaca fascicularis
                Jun. 2013 (Macaca_fascicularis_5.0/macFas5) (syntenic)
Dog - Canis lupus familiaris
                Sep. 2011 (Broad CanFam3.1/canFam3) (syntenic)
Drill - Mandrillus leucophaeus
                Mar. 2015 (Mleu.le_1.0/manLeu1) (syntenic)
Gibbon - Nomascus leucogenys
                Oct. 2012 (GGSC Nleu3.0/nomLeu3) (syntenic)
Golden snub-nosed monkey - Rhinopithecus roxellana
                Oct. 2014 (Rrox_v1/rhiRox1) (reciprocal best)
Gorilla - Gorilla gorilla gorilla
                Mar. 2016 (GSMRT3/gorGor5) (syntenic)
Green monkey - Chlorocebus sabaeus
                Mar. 2014 (Chlorocebus_sabeus 1.1/chlSab2) (syntenic)
Ma's night monkey - Aotus nancymaae
                Jun. 2017 (Anan_2.0/aotNan1) (syntenic)
Marmoset - Callithrix jacchus
                March 2009 (WUGSC 3.2/calJac3) (syntenic)
Mouse - Mus musculus
                Dec. 2011 (GRCm38/mm10) (syntenic)
Mouse lemur - Microcebus murinus
                Feb. 2017 (Mmur_3.0/micMur3) (syntenic)
Orangutan - Pongo pygmaeus abelii
                July 2007 (WUGSC 2.0.2/ponAbe2) (reciprocal best)
Pig-tailed macaque - Macaca nemestrina
                Mar. 2015 (Mnem_1.0/macNem1) (syntenic)
Proboscis monkey - Nasalis larvatus
                Nov. 2014 (Charlie1.0/nasLar1) (reciprocal best)
Rhesus - Macaca mulatta
                Nov. 2015 (BCM Mmul_8.0.1/rheMac8) (syntenic)
Sclater's lemur - Eulemur flavifrons
                Aug. 2015 (Eflavifronsk33QCA/eulFla1) (reciprocal best)
Sooty mangabey - Cercocebus atys
                Mar. 2015 (Caty_1.0/cerAty1) (syntenic)
Squirrel monkey - Saimiri boliviensis
                Oct. 2011 (Broad/saiBol1) (syntenic)
Tarsier - Tarsius syrichta
                Sep. 2013 (Tarsius_syrichta-2.0.1/tarSyr2) (reciprocal best)
White-faced sapajou - Cebus capucinus imitator
                Apr. 2016 (Cebus_imitator-1.0/cebCap1) (syntenic)

Note, the uncompressed *.wigFix.gz files are 18 Gb of data, when compressed, 
they are approximately 4.6 Gb of compressed data.  The entire set of
data in this directory is approximately 13 Gb.

To download a large file or multiple files from this directory, we recommend 
that you use rsync or ftp rather than downloading the files via our website:

   rsync -avz --progress \
        rsync:// ./


    user name: anonymous
    password: <your email address>
    go to the directory goldenPath/hg38/phyloP30way

To download multiple files from the UNIX command line, use the "mget" command. 
    mget <filename1> <filename2> ...
    - or -
    mget -a (to download all the files in the directory) 
Use the "prompt" command to toggle the interactive mode if you do not want 
to be prompted for each file that you download.

All the files in this directory are freely available for public use.
For data use restrictions regarding the genome assemblies used in this
annotation, see

References for phastCons and phyloP:

Pollard KS, Hubisz MJ, Siepel A. Detection of non-neutral substitution rates
on mammalian phylogenies. Genome Res. 2010 Jan;20(1):110-21.

Siepel A, Bejerano G, Pedersen JS, Hinrichs AS, Hou M, Rosenbloom K, Clawson
H, Spieth J, Hillier LW, Richards S, et al. Evolutionarily conserved elements
in vertebrate, insect, worm, and yeast genomes. Genome Res. 2005
Aug;15(8):1034-50.  (

      Name                    Last modified      Size  Description
Parent Directory - hg38.30way.phyloP/ 2017-11-07 13:27 - 2017-11-06 13:42 7.8G hg38.phyloP30way.mod 2017-11-06 10:43 1.2K md5sum.txt 2017-11-07 11:33 109