This directory contains alignments of the human assembly
(hg17, May 2004) to the zebrafish assembly (danRer1, Nov. 2003)
in "axt" format. For a description, see
http://genome.ucsc.edu/goldenPath/help/axt.html.
The alignments were produced by the blastz alignment program, which
is available from Webb Miller's lab at Penn State University
(http://www.bx.psu.edu/miller_lab/). The blastz scoring matrix used was:
A C G T
A 91 -90 -25 -100
C -90 100 -100 -25
G -25 -100 100 -90
T -100 -25 -90 91
with a gap open penalty of 400 and a gap extension penalty of 30. The
minimum score for an alignment to be kept was 6000 for the first pass
and 2200 for the second pass, which restricted the search space to the
regions between two alignments found in the first pass.
Each chromosome was divided into 10,000,000 base chunks for the blastz
alignments and all repeats for each organism were used as lineage-specific
repeats. Repeats were detected with Arian Smit's RepeatMasker program using
a zebrafish repeats library. The .lav format blastz output, which does not
include the sequence, was converted to .axt with lavToAxt. Low scores can
occur using the scoring matrix above and with repeats abridged; therefore,
alignments were rescored using PSU's restore_rpts program and the default
scoring matrix:
A C G T
A 91 -114 -31 -123
C -114 100 -125 -31
G -31 -125 100 -114
T -123 -31 -114 91
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If you plan to download a large file or multiple files from this
directory, we recommend you use ftp rather than downloading the files
via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to
the directory goldenPath/danRer1/vsHg17/. To download multiple files,
use the "mget" command:
mget <filename1> <filename2> ...
- or -
mget -a (to download all the files in the directory)
All the files in this directory are freely available for public use.
The Zv3 zebrafish sequence data were produced by the Zebrafish Sequencing
Group at the Sanger Institute and can be obtained directly from
ftp://ftp.sanger.ac.uk/pub/zebrafish/. All sequence data are made available
before scientific publication with the understanding that the groups
involved in generating the data intend to publish the initial large-scale
analyses of the dataset. This will include a summary detailing the data that
have beeen generated and key features of the genome identified from genomic
assembly and clone mapping/sequencing. Any redistribution of the data
should carry this notice.
Name Last modified Size Description
Parent Directory -
md5sum.txt 2004-07-20 18:42 1.3K
chrM.axt.gz 2004-06-18 13:43 221K
chr13.axt.gz 2004-06-18 13:06 2.6M
chr11.axt.gz 2004-06-18 13:05 6.4M
chr9.axt.gz 2004-06-18 13:42 6.9M
chr25.axt.gz 2004-06-18 13:30 10M
chr14.axt.gz 2004-06-18 13:06 12M
chr2.axt.gz 2004-06-18 13:31 15M
chr16.axt.gz 2004-06-18 13:12 16M
chr10.axt.gz 2004-06-18 13:04 16M
chr18.axt.gz 2004-06-18 13:14 16M
chr7.axt.gz 2004-06-18 13:40 20M
chr24.axt.gz 2004-06-18 13:30 22M
chr5.axt.gz 2004-06-18 13:38 23M
chr1.axt.gz 2004-06-18 13:17 23M
chr20.axt.gz 2004-06-18 13:18 24M
chr12.axt.gz 2004-06-18 13:06 25M
chr6.axt.gz 2004-06-18 13:39 26M
chr21.axt.gz 2004-06-18 13:19 31M
chr8.axt.gz 2004-06-18 13:41 37M
chr19.axt.gz 2004-06-18 13:16 37M
chrFinished.axt.gz 2004-06-18 13:43 39M
chr17.axt.gz 2004-06-18 13:14 47M
chr23.axt.gz 2004-06-18 13:29 48M
chr3.axt.gz 2004-06-18 13:34 90M
chr4.axt.gz 2004-06-18 13:37 103M
chr15.axt.gz 2004-06-18 13:12 150M
chr22.axt.gz 2004-06-18 13:28 281M
chrUn.axt.gz 2004-06-18 14:05 770M
chrNA.axt.gz 2004-06-18 13:56 772M